1、个人简介

杨菁，产业处负责人。中国医学科学院北京协和医学院准聘助理教授，研究员，生物医学工程、药剂学双专业博士生导师，英国Cardiff大学访问学者。天津市创新推进计划重点领域创新团队和天津市人才发展特殊支持计划高层次创新创业团队首席，北京医院客座教授。出版专著一部，发表SCI及核心期刊论文九十余篇，授权发明专利十二项。兼任国家自然科学基金、教育部、科技部、国家医疗器械技术评审中心评审专家，国际生物医学工程杂志编委。

2、代表性成果

1. Tang, Y. D., Yang, J., Zheng, Y., Li, Y., & Zeng, Y.  Application of Biomaterials in the Treatment of Cardiovascular Diseases[M]. Springer Nature 2024.

2. Huiyang Li, Lifei Ma, Ni Zhu, Xiaoyu Liang, Xinxin Tian, Kaijing Liu, Xue Fu, Xiaoli Wang, Hailing Zhang*, Houzao Chen, Qiang Liu*, and Jing Yang*. Mesenchymal stromal cells surface engineering for efficient hematopoietic reconstitution. Biomaterials, 2025. 314: 122882. (IF=14.0)

3. Kaijing Liu#, Ruihao Li#, Shusen Wang, Xue Fu, Ni Zhu, Xiaoyu Liang, Huiyang Li, Xiaoli Wang*, Le Wang*, Yongjun Li*, Jianwu Dai*, and Jing Yang*. Cu(II)-baicalein enhance paracrine effect and regenerative function of stem cells in patients with diabetes. Bioactive Materials, 2024. 36: 455-473. (IF=18)

4. Xiaoyu Liang#, Huiyang Li#, Xuanling Li, Xinxin Tian, Aiai Zhang, Qingzhi Luo, Jianwei Duan, Youlu Chen, Liyun Pang, Chen Li, Xing-Jie Liang, Yong Zeng*, and Jing Yang*. Highly sensitive H2O2-scavenging nano-bionic system for precise treatment of atherosclerosis. Acta Pharmaceutica Sinica B, 2023. 13(1): 372-389. (IF=14.7)

5. Kaijing Liu, Limei Liu, Haoyang Guo, Rong Xu, Xiaoyu Liang, Youlu Chen, Huiyang Li, Xue Fu, Xiaoli Wang*, Houzao Chen, Yongjun Li, and Jing Yang*. Redox Modulatory Cu(II)‐Baicalein Microflowers Prepared in One Step Effectively Promote Therapeutic Angiogenesis in Diabetic Mice. Advanced Healthcare Materials, 2023. 12(5): 2202010. (IF=10)

6. Youlu Chen#, Zuoguan Chen#, Jianwei Duan, Liang Gui, Huiyang Li, Xiaoyu Liang, Xinxin Tian, Kaijing Liu, Yongjun Li*, and Jing Yang*. H2O2-responsive VEGF/NGF gene co-delivery nano-system achieves stable vascularization in ischemic hindlimbs. Journal of Nanobiotechnology, 2022. 20(1). (IF=10.6)

7. Zuoguan Chen#, Jianwei Duan#, Yongpeng Diao, Youlu Chen, Xiaoyu Liang, Huiyang Li, Yuqing Miao, Qing Gao, Liang Gui, Xiaoli Wang, Jing Yang*, and Yongjun Li*. ROS-responsive capsules engineered from EGCG-Zinc networks improve therapeutic angiogenesis in mouse limb ischemia. Bioactive Materials, 2021. 6(1): 1-11. (IF=18)

8. Youlu Chen#, Yong Zeng#, Xiaowei Zhu, Lifu Miao, Xiaoyu Liang, Jianwei Duan, Huiyang Li, Xinxin Tian, Liyun Pang, Yongxiang Wei*, and Jing Yang*. Significant difference between sirolimus and paclitaxel nanoparticles in anti-proliferation effect in normoxia and hypoxia: The basis of better selection of atherosclerosis treatment. Bioactive Materials, 2021. 6(3): 880-889. (IF=18)

9. Jianwei Duan#, Zuoguan Chen#, Xiaoyu Liang, Youlu Chen, Huiyang Li, Xinxin Tian, Mingming Zhang, Xiaoli Wang, Hongfan Sun, Deling Kong, Yongjun Li*, and Jing Yang*. Construction and application of therapeutic metal-polyphenol capsule for peripheral artery disease. Biomaterials, 2020. 255: 120199. (IF=12.8)

10. Jing Yang#, Yong Zeng#, Chao Zhang, Yongxia Chen, Ziying Yang, Yongjun Li, Xigang Leng, Deling Kong, Xiaoqing Wei*, Hongfan Sun*, Cunxian Song*. The prevention of restenosis in vivo with a VEGF gene and paclitaxel co-eluting stent. Biomaterials, 2013,34(6): 1635-1643. (IF=14.0)

3、主要研究方向

课题组专注于血管损伤修复与再生，研究范围涵盖动脉粥样硬化逆转、治疗性血管生成、心肌修复、血管损伤与衰老等多个方面。已承担国自然重点及面上项目、863计划、国家九五攻关项目、国家科委、国家计生委、卫生部和天津市的重点课题及医科院科研项目在内的近五十项科研任务。

4、荣誉奖励

(1) 天津市科学技术进步奖二等奖(生物活性材料和递送系统的构建及其在动脉粥样硬化治疗中的应用) 、2021年（排名第一）、天津市人民政府(科研奖励)

(2) 天津市自然科学二等奖(介入性血管内药物和基因的靶向投递和控释体系) 、2004年(排名第二) 、天津市人民政府(科研奖励)

(3) 中华医学科学技术奖三等奖(冠心病精准诊疗创新技术的研发与转化应用)、2024年（排名第二）、中华医学会(科研奖励)

(4) 北京医学科技奖二等奖(动脉粥样硬化缺血性疾病治疗策略关键技术的创新与应用) 、2022年（排名第二）、北京医学会(科研奖励)

5、社会兼职